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Human ATP-Binding Cassette transporters ABCB1 and ABCG2 confer resistance to CUDC-101, a multi-acting inhibitor of histone deacetylase, epidermal growth factor receptor and human epidermal growth factor receptor 2.
Wu, Chung-Pu; Hsiao, Sung-Han; Su, Ching-Ya; Luo, Shi-Yu; Li, Yan-Qing; Huang, Yang-Hui; Hsieh, Chia-Hung; Huang, Chiun-Wei.
Afiliação
  • Wu CP; Department of Physiology and Pharmacology; Graduate Institute of Biomedical Sciences; Molecular Medicine Research Center, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan. Electronic address: wuchung@mail.cgu.edu.tw.
  • Hsiao SH; Graduate Institute of Biomedical Sciences.
  • Su CY; Graduate Institute of Biomedical Sciences.
  • Luo SY; Graduate Institute of Biomedical Sciences.
  • Li YQ; Department of Physiology and Pharmacology.
  • Huang YH; Molecular Medicine Research Center, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan.
  • Hsieh CH; Graduate Institute of Basic Medical Science; Department of Medical Research, China Medical University Hospital, Taichung, Taiwan.
  • Huang CW; Center for Advanced Molecular Imaging and Translation, Chang Gung Memorial Hospital, Tao-Yuan, Taiwan.
Biochem Pharmacol ; 92(4): 567-76, 2014 Dec 15.
Article em En | MEDLINE | ID: mdl-25450670
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Receptor ErbB-2 / Transportadores de Cassetes de Ligação de ATP / Inibidores de Histona Desacetilases / Receptores ErbB / Ácidos Hidroxâmicos / Proteínas de Neoplasias Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Quinazolinas / Receptor ErbB-2 / Transportadores de Cassetes de Ligação de ATP / Inibidores de Histona Desacetilases / Receptores ErbB / Ácidos Hidroxâmicos / Proteínas de Neoplasias Idioma: En Ano de publicação: 2014 Tipo de documento: Article