miR-638 regulates differentiation and proliferation in leukemic cells by targeting cyclin-dependent kinase 2.

Lin, Yi; Li, Dengju; Liang, Qing; Liu, Shangqing; Zuo, Xuelan; Li, Lin; Sun, Xuemei; Li, Wenxin; Guo, Mingxiong; Huang, Zan

Lin, Yi; Li, Dengju; Liang, Qing; Liu, Shangqing; Zuo, Xuelan; Li, Lin; Sun, Xuemei; Li, Wenxin; Guo, Mingxiong; Huang, Zan.

Afiliação

Lin Y; From the College of Life Sciences, Wuhan University, Wuhan, Hubei, China, 430072.
Li D; the Department of Hematology, Tongji Hospital of Huazhong Technology University, Wuhan, Hubei, China, 430030.
Liang Q; the Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China, 430071, and.
Liu S; the Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China, 430071, and.
Zuo X; the Department of Hematology, Zhongnan Hospital, Wuhan University, Wuhan, Hubei, China, 430071, and.
Li L; the Department of Hematology, Jiangsu Province Hospital of Traditional Chinese Medicine (TCM), Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China, 210029.
Sun X; the Department of Hematology, Jiangsu Province Hospital of Traditional Chinese Medicine (TCM), Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China, 210029.
Li W; From the College of Life Sciences, Wuhan University, Wuhan, Hubei, China, 430072.
Guo M; From the College of Life Sciences, Wuhan University, Wuhan, Hubei, China, 430072, guomx@whu.edu.cn.
Huang Z; From the College of Life Sciences, Wuhan University, Wuhan, Hubei, China, 430072, z-huang@whu.edu.cn.

J Biol Chem ; 290(3): 1818-28, 2015 Jan 16.

Article em En | MEDLINE | ID: mdl-25451924

Assuntos

Quinase 2 Dependente de Ciclina/metabolismo; Regulação Leucêmica da Expressão Gênica; Leucemia Mieloide Aguda/metabolismo; MicroRNAs/metabolismo; Sequência de Bases; Biomarcadores Tumorais/metabolismo; Diferenciação Celular; Linhagem Celular Tumoral; Proliferação de Células; Quinase 2 Dependente de Ciclina/genética; Células HEK293; Células HL-60; Hematopoese; Humanos; MicroRNAs/genética; Dados de Sequência Molecular; Oligonucleotídeos/genética; Fenótipo; Homologia de Sequência do Ácido Nucleico; Acetato de Tetradecanoilforbol; Regulação para Cima

Palavras-chave

Cyclin-dependent Kinase (CDK); Differentiation; Hematopoiesis; Leukemia; MicroRNA (miRNA)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Leucêmica da Expressão Gênica / MicroRNAs / Quinase 2 Dependente de Ciclina Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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