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Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: disease mechanisms and pharmacological rescue.
Zhang, Miao; D'Aniello, Cristina; Verkerk, Arie O; Wrobel, Eva; Frank, Stefan; Ward-van Oostwaard, Dorien; Piccini, Ilaria; Freund, Christian; Rao, Jyoti; Seebohm, Guiscard; Atsma, Douwe E; Schulze-Bahr, Eric; Mummery, Christine L; Greber, Boris; Bellin, Milena.
Afiliação
  • Zhang M; Human Stem Cell Pluripotency Group, Max Planck Institute for Molecular Biomedicine, D-48149 Münster, Germany; Chemical Genomics Centre of the Max Planck Society, 44227 Dortmund, Germany; Departments of.
  • D'Aniello C; Anatomy and Embryology and.
  • Verkerk AO; Department of Anatomy, Embryology and Physiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, 1105 AZ, The Netherlands; and.
  • Wrobel E; Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, D-48149 Münster, Germany.
  • Frank S; Human Stem Cell Pluripotency Group, Max Planck Institute for Molecular Biomedicine, D-48149 Münster, Germany; Chemical Genomics Centre of the Max Planck Society, 44227 Dortmund, Germany; Departments of.
  • Ward-van Oostwaard D; Anatomy and Embryology and.
  • Piccini I; Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, D-48149 Münster, Germany.
  • Freund C; Anatomy and Embryology and.
  • Rao J; Human Stem Cell Pluripotency Group, Max Planck Institute for Molecular Biomedicine, D-48149 Münster, Germany; Chemical Genomics Centre of the Max Planck Society, 44227 Dortmund, Germany; Departments of.
  • Seebohm G; Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, D-48149 Münster, Germany.
  • Atsma DE; Cardiology, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands;
  • Schulze-Bahr E; Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, D-48149 Münster, Germany.
  • Mummery CL; Anatomy and Embryology and.
  • Greber B; Human Stem Cell Pluripotency Group, Max Planck Institute for Molecular Biomedicine, D-48149 Münster, Germany; Chemical Genomics Centre of the Max Planck Society, 44227 Dortmund, Germany; Departments of boris.greber@mpi-muenster.mpg.de m.bellin@lumc.nl.
  • Bellin M; Anatomy and Embryology and boris.greber@mpi-muenster.mpg.de m.bellin@lumc.nl.
Proc Natl Acad Sci U S A ; 111(50): E5383-92, 2014 Dec 16.
Article em En | MEDLINE | ID: mdl-25453094
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Síndrome de Jervell-Lange Nielsen / Canal de Potássio KCNQ1 / Células-Tronco Pluripotentes Induzidas / Modelos Biológicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fenótipo / Síndrome de Jervell-Lange Nielsen / Canal de Potássio KCNQ1 / Células-Tronco Pluripotentes Induzidas / Modelos Biológicos Idioma: En Ano de publicação: 2014 Tipo de documento: Article