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A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway.
Helling, Bianca; König, Martin; Dälken, Benjamin; Engling, Andre; Krömer, Wolfgang; Heim, Katharina; Wallmeier, Holger; Haas, Jürgen; Wildemann, Brigitte; Fritz, Brigitte; Jonuleit, Helmut; Kubach, Jan; Dingermann, Theodor; Radeke, Heinfried H; Osterroth, Frank; Uherek, Christoph; Czeloth, Niklas; Schüttrumpf, Jörg.
Afiliação
  • Helling B; Biotest AG, Dreieich, Germany.
  • König M; Biotest AG, Dreieich, Germany.
  • Dälken B; Biotest AG, Dreieich, Germany.
  • Engling A; Biotest AG, Dreieich, Germany.
  • Krömer W; Biotest AG, Dreieich, Germany.
  • Heim K; Biotest AG, Dreieich, Germany.
  • Wallmeier H; Condor Scientific Computing and Consulting, Sulzbach, Germany.
  • Haas J; Division of Molecular Neuroimmunology, Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
  • Wildemann B; Division of Molecular Neuroimmunology, Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
  • Fritz B; Division of Molecular Neuroimmunology, Department of Neurology, University Hospital Heidelberg, Heidelberg, Germany.
  • Jonuleit H; Department of Dermatology, Johannes Gutenberg University, Mainz, Germany.
  • Kubach J; Department of Dermatology, Johannes Gutenberg University, Mainz, Germany.
  • Dingermann T; Institute of Pharmaceutical Biology, Goethe University Frankfurt, Frankfurt, Germany.
  • Radeke HH; Institute of Pharmacology and Toxicology, Clinic of the Goethe University, Frankfurt, Germany.
  • Osterroth F; Biotest AG, Dreieich, Germany.
  • Uherek C; Biotest AG, Dreieich, Germany.
  • Czeloth N; Biotest AG, Dreieich, Germany.
  • Schüttrumpf J; Biotest AG, Dreieich, Germany.
Immunol Cell Biol ; 93(4): 396-405, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25512343
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD4 / Subpopulações de Linfócitos T / Linfócitos T Reguladores / Epitopos de Linfócito B / Imunossupressores / Anticorpos Monoclonais Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antígenos CD4 / Subpopulações de Linfócitos T / Linfócitos T Reguladores / Epitopos de Linfócito B / Imunossupressores / Anticorpos Monoclonais Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Alemanha