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Proteomics-based metabolic modeling reveals that fatty acid oxidation (FAO) controls endothelial cell (EC) permeability.
Patella, Francesca; Schug, Zachary T; Persi, Erez; Neilson, Lisa J; Erami, Zahra; Avanzato, Daniele; Maione, Federica; Hernandez-Fernaud, Juan R; Mackay, Gillian; Zheng, Liang; Reid, Steven; Frezza, Christian; Giraudo, Enrico; Fiorio Pla, Alessandra; Anderson, Kurt; Ruppin, Eytan; Gottlieb, Eyal; Zanivan, Sara.
Afiliação
  • Patella F; From the ‡Vascular Proteomics Lab.
  • Schug ZT; §Apoptosis and Tumour Metabolism Lab.
  • Persi E; ¶The Blavatnik School of Computer Science, Tel Aviv University, 69978 Tel Aviv, Israel; ‖School of Physics and Astronomy, Tel Aviv University, 69978 Tel Aviv, Israel;
  • Neilson LJ; From the ‡Vascular Proteomics Lab.
  • Erami Z; **Tumour Cell Migration Lab, Cancer Research UK Beatson Institute, Switchback Road, G61 1BD, Glasgow, UK;
  • Avanzato D; ‡‡Department of Life Sciences and Systems Biology, University of Torino, Via Accademia Albertina 13, 10123 Torino, Italy;
  • Maione F; §§Laboratory of Transgenic Mouse Models, Candiolo Cancer Institute - FPO, IRCCS, Str prov 142 Km 3.95, 10060, Candiolo, Torino, Italy; ¶¶Department of Science and Drug Technology, University of Torino, Via P. Giuria, 9 - 10125 Torino, Italy;
  • Hernandez-Fernaud JR; From the ‡Vascular Proteomics Lab.
  • Mackay G; §Apoptosis and Tumour Metabolism Lab.
  • Zheng L; §Apoptosis and Tumour Metabolism Lab.
  • Reid S; From the ‡Vascular Proteomics Lab.
  • Frezza C; ‖‖MRC Cancer Unit, Cambridge Biomedical Campus, University of Cambridge, Hutchison/MRC Research Centre, Box 197, CB2 0XZ, Cambridge, UK;
  • Giraudo E; §§Laboratory of Transgenic Mouse Models, Candiolo Cancer Institute - FPO, IRCCS, Str prov 142 Km 3.95, 10060, Candiolo, Torino, Italy; ¶¶Department of Science and Drug Technology, University of Torino, Via P. Giuria, 9 - 10125 Torino, Italy;
  • Fiorio Pla A; ‡‡Department of Life Sciences and Systems Biology, University of Torino, Via Accademia Albertina 13, 10123 Torino, Italy;
  • Anderson K; **Tumour Cell Migration Lab, Cancer Research UK Beatson Institute, Switchback Road, G61 1BD, Glasgow, UK;
  • Ruppin E; ¶The Blavatnik School of Computer Science, Tel Aviv University, 69978 Tel Aviv, Israel; Sackler School of Medicine, and Department of Molecular Microbiology and Biotechnology, Faculty of Life Sciences, Tel-Aviv University, 69978 Tel Aviv, Israel.
  • Gottlieb E; §Apoptosis and Tumour Metabolism Lab.
  • Zanivan S; From the ‡Vascular Proteomics Lab, s.zanivan@beatson.gla.ac.uk.
Mol Cell Proteomics ; 14(3): 621-34, 2015 Mar.
Article em En | MEDLINE | ID: mdl-25573745
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carnitina O-Palmitoiltransferase / Proteômica / Células Endoteliais / Ácidos Graxos / Metaboloma / Modelos Biológicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carnitina O-Palmitoiltransferase / Proteômica / Células Endoteliais / Ácidos Graxos / Metaboloma / Modelos Biológicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article