A newly developed anti-Mucin 13 monoclonal antibody targets pancreatic ductal adenocarcinoma cells.

Nishii, Yukari; Yamaguchi, Miki; Kimura, Yasutoshi; Hasegawa, Tadashi; Aburatani, Hiroyuki; Uchida, Hiroaki; Hirata, Koichi; Sakuma, Yuji

Nishii, Yukari; Yamaguchi, Miki; Kimura, Yasutoshi; Hasegawa, Tadashi; Aburatani, Hiroyuki; Uchida, Hiroaki; Hirata, Koichi; Sakuma, Yuji.

Afiliação

Nishii Y; Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Yamaguchi M; Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.
Kimura Y; Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, Sapporo, Japan.
Hasegawa T; Department of Surgical Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Aburatani H; Genome Science Division, Research Center for Advanced Science and Technology, The University of Tokyo, Tokyo, Japan.
Uchida H; Laboratory of Oncology, Department of Life Sciences, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan.
Hirata K; Department of Surgery, Surgical Oncology and Science, Sapporo Medical University School of Medicine, Sapporo, Japan.
Sakuma Y; Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan.

Int J Oncol ; 46(4): 1781-7, 2015 Apr.

Article em En | MEDLINE | ID: mdl-25672256

Assuntos

Anticorpos Monoclonais/administração & dosagem; Antineoplásicos/administração & dosagem; Carcinoma Ductal Pancreático/tratamento farmacológico; Imunoconjugados/administração & dosagem; Mucinas/metabolismo; Neoplasias Pancreáticas/tratamento farmacológico; Adulto; Idoso; Idoso de 80 Anos ou mais; Animais; Anticorpos Monoclonais/uso terapêutico; Antineoplásicos/uso terapêutico; Carcinoma Ductal Pancreático/metabolismo; Linhagem Celular Tumoral; Feminino; Humanos; Imunoconjugados/uso terapêutico; Masculino; Camundongos; Pessoa de Meia-Idade; Mucinas/antagonistas & inibidores; Neoplasias Pancreáticas/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Imunoconjugados / Carcinoma Ductal Pancreático / Anticorpos Monoclonais / Mucinas / Antineoplásicos Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão

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