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Effect of roflumilast on exacerbations in patients with severe chronic obstructive pulmonary disease uncontrolled by combination therapy (REACT): a multicentre randomised controlled trial.
Martinez, Fernando J; Calverley, Peter M A; Goehring, Udo-Michael; Brose, Manja; Fabbri, Leonardo M; Rabe, Klaus F.
Afiliação
  • Martinez FJ; Weill Cornell Medical College, New York, NY, USA; University of Michigan Health System, Ann Arbor, MI, USA. Electronic address: fmartine@med.umich.edu.
  • Calverley PM; Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
  • Goehring UM; Takeda Development Centre Europe Ltd, London, UK.
  • Brose M; Takeda Pharmaceuticals International GmbH, Zurich, Switzerland.
  • Fabbri LM; University of Modena and Reggio Emilia, Modena, Italy.
  • Rabe KF; LungenClinic Grosshansdorf, Airway Research Center North, Member of the German Center for Lung Research (DZL), Grosshansdorf, Germany; Department of Medicine, Christian-Albrechts University Kiel, Kiel, Germany.
Lancet ; 385(9971): 857-66, 2015 Mar 07.
Article em En | MEDLINE | ID: mdl-25684586

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Anti-Inflamatórios não Esteroides / Doença Pulmonar Obstrutiva Crônica / Inibidores da Fosfodiesterase 4 / Aminopiridinas Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Benzamidas / Anti-Inflamatórios não Esteroides / Doença Pulmonar Obstrutiva Crônica / Inibidores da Fosfodiesterase 4 / Aminopiridinas Idioma: En Ano de publicação: 2015 Tipo de documento: Article