Adipogenic Differentiation of hMSCs is Mediated by Recruitment of IGF-1r Onto the Primary Cilium Associated With Cilia Elongation.

Dalbay, Melis T; Thorpe, Stephen D; Connelly, John T; Chapple, J Paul; Knight, Martin M

Dalbay, Melis T; Thorpe, Stephen D; Connelly, John T; Chapple, J Paul; Knight, Martin M.

Afiliação

Dalbay MT; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.
Thorpe SD; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.
Connelly JT; Institute of Bioengineering and Institute of Cellular and Molecular Sciences, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary, University of London, London, , UK.
Chapple JP; Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.
Knight MM; Institute of Bioengineering and School of Engineering and Materials Science, Queen Mary University of London, London, United Kingdom.

Stem Cells ; 33(6): 1952-61, 2015 Jun.

Article em En | MEDLINE | ID: mdl-25693948

Assuntos

Adipócitos/citologia; Adipogenia/fisiologia; Células-Tronco Mesenquimais/citologia; Receptor IGF Tipo 1/metabolismo; Ciclo Celular/fisiologia; Células Cultivadas; Cílios/metabolismo; Humanos; Transdução de Sinais

Palavras-chave

Adipogenic differentiation; Chondrogenic differentiation; Cilia; Human mesenchymal stem cell; IGF-1 receptor; Osteogenic differentiation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor IGF Tipo 1 / Adipócitos / Adipogenia / Células-Tronco Mesenquimais Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido

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