Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation.

Mirbaha, Hilda; Holmes, Brandon B; Sanders, David W; Bieschke, Jan; Diamond, Marc I

Mirbaha, Hilda; Holmes, Brandon B; Sanders, David W; Bieschke, Jan; Diamond, Marc I.

Afiliação

Mirbaha H; From the Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
Holmes BB; From the Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
Sanders DW; From the Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390 and.
Bieschke J; the Department of Biomedical Engineering, Washington University, St. Louis, Missouri 63130.
Diamond MI; From the Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, Texas 75390 and Marc.Diamond@UTSouthwestern.edu.

J Biol Chem ; 290(24): 14893-903, 2015 Jun 12.

Article em En | MEDLINE | ID: mdl-25887395

Assuntos

Biopolímeros/metabolismo; Proteínas tau/metabolismo; Cromatografia em Gel; Células HEK293; Humanos; Espectrometria de Fluorescência

Palavras-chave

Tau protein; amyloid; endocytosis; neurodegenerative disease; prion; structure

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biopolímeros / Proteínas tau Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Biopolímeros / Proteínas tau Idioma: En Ano de publicação: 2015 Tipo de documento: Article