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PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.
Park, Hyo Jin; Park, Joon Seok; Jeong, Yun Hee; Son, Jimin; Ban, Young Ho; Lee, Byoung-Hee; Chen, Lieping; Chang, Jun; Chung, Doo Hyun; Choi, Inhak; Ha, Sang-Jun.
Afiliação
  • Park HJ; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea;
  • Park JS; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea;
  • Jeong YH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea;
  • Son J; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea;
  • Ban YH; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea;
  • Lee BH; Division of Biological Resources Coordination, National Institute of Biological Resources, Environmental Research Complex, Incheon 404-170, Korea;
  • Chen L; Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520;
  • Chang J; Division of Life and Pharmaceutical Sciences, Ewha Womans University, Seoul 120-750, Korea;
  • Chung DH; Department of Pathology, College of Medicine, Seoul National University, Seoul 110-799, Korea; and.
  • Choi I; Department of Microbiology and Immunology, Inje University College of Medicine, Busan 633-165, Korea.
  • Ha SJ; Department of Biochemistry, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea; sjha@yonsei.ac.kr.
J Immunol ; 194(12): 5801-11, 2015 Jun 15.
Article em En | MEDLINE | ID: mdl-25934860
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Viroses / Subpopulações de Linfócitos T / Imunomodulação / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Viroses / Subpopulações de Linfócitos T / Imunomodulação / Antígeno B7-H1 / Receptor de Morte Celular Programada 1 Idioma: En Ano de publicação: 2015 Tipo de documento: Article