Porphyromonas gingivalis-derived RgpA-Kgp Complex Activates the Macrophage Urokinase Plasminogen Activator System: IMPLICATIONS FOR PERIODONTITIS.

Fleetwood, Andrew J; O'Brien-Simpson, Neil M; Veith, Paul D; Lam, Roselind S; Achuthan, Adrian; Cook, Andrew D; Singleton, William; Lund, Ida K; Reynolds, Eric C; Hamilton, John A

Fleetwood, Andrew J; O'Brien-Simpson, Neil M; Veith, Paul D; Lam, Roselind S; Achuthan, Adrian; Cook, Andrew D; Singleton, William; Lund, Ida K; Reynolds, Eric C; Hamilton, John A.

Afiliação

Fleetwood AJ; From the Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia, andrew.fleetwood@unimelb.edu.au.
O'Brien-Simpson NM; the Oral Health Cooperative Research Centre, Melbourne Dental School, University of Melbourne, Victoria 3010, Australia, and.
Veith PD; the Oral Health Cooperative Research Centre, Melbourne Dental School, University of Melbourne, Victoria 3010, Australia, and.
Lam RS; the Oral Health Cooperative Research Centre, Melbourne Dental School, University of Melbourne, Victoria 3010, Australia, and.
Achuthan A; From the Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.
Cook AD; From the Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.
Singleton W; the Oral Health Cooperative Research Centre, Melbourne Dental School, University of Melbourne, Victoria 3010, Australia, and.
Lund IK; the Finsen Laboratory, Rigshospitalet and the Biotech Research and Innovation Centre, Copenhagen University, 1165 Copenhagen, Denmark.
Reynolds EC; the Oral Health Cooperative Research Centre, Melbourne Dental School, University of Melbourne, Victoria 3010, Australia, and.
Hamilton JA; From the Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia.

J Biol Chem ; 290(26): 16031-42, 2015 Jun 26.

Article em En | MEDLINE | ID: mdl-25979345

Assuntos

Adesinas Bacterianas/metabolismo; Cisteína Endopeptidases/metabolismo; Macrófagos/enzimologia; Periodontite/enzimologia; Porphyromonas gingivalis/enzimologia; Ativador de Plasminogênio Tipo Uroquinase/metabolismo; Adesinas Bacterianas/genética; Animais; Células Cultivadas; Cisteína Endopeptidases/genética; Ativação Enzimática; Feminino; Cisteína Endopeptidases Gingipaínas; Interações Hospedeiro-Patógeno; Humanos; Macrófagos/microbiologia; Camundongos; Camundongos Endogâmicos C57BL; Periodontite/genética; Periodontite/microbiologia; Porphyromonas gingivalis/genética; Ligação Proteica; Ativador de Plasminogênio Tipo Uroquinase/genética

Palavras-chave

extracellular matrix; macrophage; periodontal disease; plasmin; plasminogen

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Periodontite / Cisteína Endopeptidases / Ativador de Plasminogênio Tipo Uroquinase / Porphyromonas gingivalis / Adesinas Bacterianas / Macrófagos Idioma: En Ano de publicação: 2015 Tipo de documento: Article

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