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Large Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella pneumoniae Traced to Clonal Expansion of an mgrB Deletion Mutant.
Giani, Tommaso; Arena, Fabio; Vaggelli, Guendalina; Conte, Viola; Chiarelli, Adriana; Henrici De Angelis, Lucia; Fornaini, Rossella; Grazzini, Maddalena; Niccolini, Fabrizio; Pecile, Patrizia; Rossolini, Gian Maria.
Afiliação
  • Giani T; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Arena F; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Vaggelli G; Clinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy.
  • Conte V; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Chiarelli A; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Henrici De Angelis L; Department of Medical Biotechnologies, University of Siena, Siena, Italy.
  • Fornaini R; Hospital Pharmacy Unit, Florence Careggi University Hospital, Florence, Italy.
  • Grazzini M; Hospital Medical Direction, Florence Careggi University Hospital, Florence, Italy.
  • Niccolini F; Hospital Medical Direction, Florence Careggi University Hospital, Florence, Italy.
  • Pecile P; Clinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy.
  • Rossolini GM; Department of Medical Biotechnologies, University of Siena, Siena, Italy Clinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy Don Carlo Gnocchi Foundation, Florence, It
J Clin Microbiol ; 53(10): 3341-4, 2015 Oct.
Article em En | MEDLINE | ID: mdl-26202124
We describe a large hospital outbreak (93 bloodstream infections) of colistin-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae isolates which was mirrored by increased colistin consumption. The outbreak was mostly traced to the clonal expansion of an mgrB deletion mutant of an ST512 strain that produced KPC-3.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Beta-Lactamases / Infecções por Klebsiella / Surtos de Doenças / Colistina / Farmacorresistência Bacteriana / Klebsiella pneumoniae / Antibacterianos Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Itália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Bactérias / Beta-Lactamases / Infecções por Klebsiella / Surtos de Doenças / Colistina / Farmacorresistência Bacteriana / Klebsiella pneumoniae / Antibacterianos Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Itália