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Antibodies targeting human IL1RAP (IL1R3) show therapeutic effects in xenograft models of acute myeloid leukemia.
Ågerstam, Helena; Karlsson, Christine; Hansen, Nils; Sandén, Carl; Askmyr, Maria; von Palffy, Sofia; Högberg, Carl; Rissler, Marianne; Wunderlich, Mark; Juliusson, Gunnar; Richter, Johan; Sjöström, Kjell; Bhatia, Ravi; Mulloy, James C; Järås, Marcus; Fioretos, Thoas.
Afiliação
  • Ågerstam H; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden; helena.agerstam@med.lu.se thoas.fioretos@med.lu.se.
  • Karlsson C; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Hansen N; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Sandén C; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Askmyr M; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • von Palffy S; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Högberg C; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Rissler M; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Wunderlich M; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229;
  • Juliusson G; Department of Hematology and Vascular Disorders, Skåne University Hospital, 22185 Lund, Sweden;
  • Richter J; Department of Hematology and Vascular Disorders, Skåne University Hospital, 22185 Lund, Sweden;
  • Sjöström K; Innovagen AB, 22370 Lund, Sweden;
  • Bhatia R; Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Mulloy JC; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45229;
  • Järås M; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden;
  • Fioretos T; Department of Clinical Genetics, Lund University, 22184 Lund, Sweden; helena.agerstam@med.lu.se thoas.fioretos@med.lu.se.
Proc Natl Acad Sci U S A ; 112(34): 10786-91, 2015 Aug 25.
Article em En | MEDLINE | ID: mdl-26261316
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Proteína Acessória do Receptor de Interleucina-1 / Anticorpos Monoclonais / Proteínas de Neoplasias Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Proteína Acessória do Receptor de Interleucina-1 / Anticorpos Monoclonais / Proteínas de Neoplasias Idioma: En Ano de publicação: 2015 Tipo de documento: Article