Prazosin-Conjugated Matrices Based on Biodegradable Polymers and &#945;-Amino Acids--Synthesis, Characterization, and in Vitro Release Study.

Oledzka, Ewa; Sawicka, Anna; Sobczak, Marcin; Nalecz-Jawecki, Grzegorz; Skrzypczak, Agata; Kolodziejski, Waclaw

Prazosin-Conjugated Matrices Based on Biodegradable Polymers and α-Amino Acids--Synthesis, Characterization, and in Vitro Release Study.

Oledzka, Ewa; Sawicka, Anna; Sobczak, Marcin; Nalecz-Jawecki, Grzegorz; Skrzypczak, Agata; Kolodziejski, Waclaw.

Afiliação

Oledzka E; Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, Warsaw 02-097, Poland. eoledzka@wum.edu.pl.
Sawicka A; Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, Warsaw 02-097, Poland. sawicka.anna.maria@gmail.com.
Sobczak M; Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, Warsaw 02-097, Poland. marcin.sobczak@wp.pl.
Nalecz-Jawecki G; Department of Environmental Health Science, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, Warsaw 02-097, Poland. gnalecz@wum.edu.pl.
Skrzypczak A; Department of Environmental Health Science, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, Warsaw 02-097, Poland. agata.skrzypczak@wum.edu.pl.
Kolodziejski W; Department of Inorganic and Analytical Chemistry, Faculty of Pharmacy with the Laboratory Medicine Division, Medical University of Warsaw, Banacha 1, Warsaw 02-097, Poland. waclaw.kolodziejski@wum.edu.pl.

Molecules ; 20(8): 14533-51, 2015 Aug 12.

Article em En | MEDLINE | ID: mdl-26274943

Assuntos

Aminoácidos/química; Sistemas de Liberação de Medicamentos/métodos; Poliésteres/química; Prazosina/análogos & derivados; Prazosina/química; Antagonistas de Receptores Adrenérgicos alfa 1/síntese química; Antagonistas de Receptores Adrenérgicos alfa 1/química; Aliivibrio fischeri/efeitos dos fármacos; Anti-Hipertensivos/síntese química; Anti-Hipertensivos/química; Arginina/química; Varredura Diferencial de Calorimetria; Caproatos/química; Cilióforos/efeitos dos fármacos; Citrulina/química; Imidazóis/química; Lactonas/química; Espectroscopia de Ressonância Magnética; Ressonância Magnética Nuclear Biomolecular; Prazosina/síntese química; Prazosina/farmacologia

Palavras-chave

biodegradable polymers; controlled release/delivery; cytotoxicity; macromolecular drug delivery; polymeric drug delivery system; prazosin

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Poliésteres / Prazosina / Sistemas de Liberação de Medicamentos / Aminoácidos Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Polônia

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