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Lymphoblastoid cell lines reveal associations of adult DNA methylation with childhood and current adversity that are distinct from whole blood associations.
Suderman, Matthew; Pappas, Jane J; Borghol, Nada; Buxton, Jessica L; McArdle, Wendy L; Ring, Susan M; Hertzman, Clyde; Power, Chris; Szyf, Moshe; Pembrey, Marcus.
Afiliação
  • Suderman M; MRC Integrative Epidemiology Unit (IEU), School of Social and Community Medicine, University of Bristol, Bristol, UK, matthew.suderman@bristol.ac.uk.
  • Pappas JJ; Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada, Department of Physiology, University of Toronto, Toronto, Ontario, Canada.
  • Borghol N; Department of Biochemistry, Faculty of Sciences I, Lebanese University, Beirut, Lebanon.
  • Buxton JL; Centre for Cardiovascular Genetics, Institute of Cardiovascular Science, University College London, London, UK.
  • McArdle WL; School of Social and Community Medicine, University of Bristol, Bristol, UK.
  • Ring SM; MRC Integrative Epidemiology Unit (IEU), School of Social and Community Medicine, University of Bristol, Bristol, UK.
  • Hertzman C; Human Early Learning Partnership, University of British Columbia, British Columbia, Canada.
  • Power C; Population, Policy and Practice, UCL Institute of Child Health, London, UK.
  • Szyf M; Department of Physiology, University of Toronto, Toronto, Ontario, Canada, Sackler Program for Epigenetics & Developmental Psychobiology, McGill University, Montreal, Quebec, Canada and.
  • Pembrey M; Genetics and Epigenetics in Health and Disease Section, UCL Institute of Child Health, UK.
Int J Epidemiol ; 44(4): 1331-40, 2015 Aug.
Article em En | MEDLINE | ID: mdl-26351305

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Metilação de DNA / Epigênese Genética / Sobreviventes Adultos de Maus-Tratos Infantis / Uso de Tabaco Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Metilação de DNA / Epigênese Genética / Sobreviventes Adultos de Maus-Tratos Infantis / Uso de Tabaco Idioma: En Ano de publicação: 2015 Tipo de documento: Article