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Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases.
Kai, Kazuharu; Kondo, Kimie; Wang, Xiaoping; Xie, Xuemei; Pitner, Mary K; Reyes, Monica E; Torres-Adorno, Angie M; Masuda, Hiroko; Hortobagyi, Gabriel N; Bartholomeusz, Chandra; Saya, Hideyuki; Tripathy, Debu; Sen, Subrata; Ueno, Naoto T.
Afiliação
  • Kai K; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. nueno@mdanderson.org kkai@mdanderson.org.
  • Kondo K; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Wang X; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Xie X; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Pitner MK; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Reyes ME; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Torres-Adorno AM; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Masuda H; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Hortobagyi GN; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Bartholomeusz C; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Saya H; Division of Gene Regulation, Institute for Advanced Medical Research, School of Medicine, Keio University, Tokyo, Japan.
  • Tripathy D; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Sen S; Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
  • Ueno NT; Section of Translational Breast Cancer Research, The University of Texas MD Anderson Cancer Center, Houston, Texas. Department of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. nueno@mdanderson.org kkai@mdanderson.org.
Mol Cancer Ther ; 14(12): 2687-99, 2015 Dec.
Article em En | MEDLINE | ID: mdl-26443806

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Inibidores de Proteínas Quinases / Neoplasias de Mama Triplo Negativas / Aurora Quinase A / Aurora Quinase B / Indazóis Idioma: En Ano de publicação: 2015 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Inibidores de Proteínas Quinases / Neoplasias de Mama Triplo Negativas / Aurora Quinase A / Aurora Quinase B / Indazóis Idioma: En Ano de publicação: 2015 Tipo de documento: Article