Anticonvulsant and behavioral effects observed in mice following treatment with an ester derivative of ferulic acid: Isopentyl ferulate.

Machado, Keylla C; Oliveira, George Laylson S; Machado, Kátia C; Islam, Md Torequl; Junior, Antonio Luiz G; De Sousa, Damião P; Freitas, Rivelilson M

Machado, Keylla C; Oliveira, George Laylson S; Machado, Kátia C; Islam, Md Torequl; Junior, Antonio Luiz G; De Sousa, Damião P; Freitas, Rivelilson M.

Afiliação

Machado KC; Post-Graduation Program in Pharmacology, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil.
Oliveira GL; Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutical Sciences, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil.
Machado KC; Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutical Sciences, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil.
Islam MT; Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutical Sciences, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil.
Junior AL; Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutical Sciences, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil.
De Sousa DP; Department of Pharmaceutical Science, Federal University of Paraíba, CEP 58.051-900, João Pessoa, Paraíba, Brazil.
Freitas RM; Post-Graduation Program in Pharmacology, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil; Laboratory of Research in Experimental Neurochemistry of Post-Graduation Program in Pharmaceutical Sciences, Federal University of Piauí, CEP 64.049-550, Teresina, Piauí, Brazil. Electronic

Chem Biol Interact ; 242: 273-9, 2015 Dec 05.

Article em En | MEDLINE | ID: mdl-26456888

Assuntos

Anticonvulsivantes/farmacologia; Comportamento Animal/efeitos dos fármacos; Ácidos Cumáricos/farmacologia; Animais; Anticonvulsivantes/química; Anticonvulsivantes/uso terapêutico; Ácidos Cumáricos/química; Ácidos Cumáricos/uso terapêutico; Masculino; Camundongos; Atividade Motora/efeitos dos fármacos; Relaxamento Muscular/efeitos dos fármacos; Pentilenotetrazol/efeitos adversos; Pilocarpina/efeitos adversos; Convulsões/induzido quimicamente; Convulsões/tratamento farmacológico; Convulsões/fisiopatologia

Palavras-chave

Anticonvulsant effect; Epileptic seizures; Isopentyl ferulate; Locomotor activity; Motor coordination

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Comportamento Animal / Ácidos Cumáricos / Anticonvulsivantes Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Brasil

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