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The unique transcriptional response produced by concurrent estrogen and progesterone treatment in breast cancer cells results in upregulation of growth factor pathways and switching from a Luminal A to a Basal-like subtype.
Need, Eleanor F; Selth, Luke A; Trotta, Andrew P; Leach, Damien A; Giorgio, Lauren; O'Loughlin, Melissa A; Smith, Eric; Gill, Peter G; Ingman, Wendy V; Graham, J Dinny; Buchanan, Grant.
Afiliação
  • Need EF; Cancer Biology Group, The Basil Hetzel Institute for Translational Health Research, School of Medicine, The University of Adelaide, DX465701, 28 Woodville Road, Woodville South, 5011, South Australia, Australia. Eleanor.need@adelaide.edu.au.
  • Selth LA; Dame Roma Mitchell Cancer Research Laboratories and Adelaide Prostate Cancer Research Centre, The University of Adelaide, Adelaide, South Australia, Australia. Luke.selth@adelaide.edu.au.
  • Trotta AP; Freemasons Foundation Centre for Men's Health, The University of Adelaide, Adelaide, South Australia, Australia. Luke.selth@adelaide.edu.au.
  • Leach DA; Cancer Biology Group, The Basil Hetzel Institute for Translational Health Research, School of Medicine, The University of Adelaide, DX465701, 28 Woodville Road, Woodville South, 5011, South Australia, Australia. Trotta.andrew@gmail.com.
  • Giorgio L; Present address: Icahn School of Medicine at Mount Sinai, Department of Oncological Sciences, Manhattan, New York, USA. Trotta.andrew@gmail.com.
  • O'Loughlin MA; Cancer Biology Group, The Basil Hetzel Institute for Translational Health Research, School of Medicine, The University of Adelaide, DX465701, 28 Woodville Road, Woodville South, 5011, South Australia, Australia. Damien.leach@adelaide.edu.au.
  • Smith E; Cancer Biology Group, The Basil Hetzel Institute for Translational Health Research, School of Medicine, The University of Adelaide, DX465701, 28 Woodville Road, Woodville South, 5011, South Australia, Australia. lauren.giorgio@gmail.com.
  • Gill PG; Cancer Biology Group, The Basil Hetzel Institute for Translational Health Research, School of Medicine, The University of Adelaide, DX465701, 28 Woodville Road, Woodville South, 5011, South Australia, Australia. melol@adam.com.au.
  • Ingman WV; Solid Cancer Regulation Research Group, The Basil Hetzel Institute for Translational Health Research Discipline of Surgery, The University of Adelaide, South Australia, Australia. Eric.smith@adelaide.edu.au.
  • Graham JD; School of Medicine, Department of Surgery, The University of Adelaide, Adelaide, South Australia, Australia. grantley.gill@adelaide.edu.au.
  • Buchanan G; School of Medicine at The Queen Elizabeth Hospital, University of Adelaide, South Australia, Australia. wendy.ingman@adelaide.edu.au.
BMC Cancer ; 15: 791, 2015 Oct 24.
Article em En | MEDLINE | ID: mdl-26498662
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progesterona / Neoplasias da Mama / Ativação Transcricional / Estrogênios / Receptores ErbB Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Progesterona / Neoplasias da Mama / Ativação Transcricional / Estrogênios / Receptores ErbB Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Austrália