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Discovery of an orally bioavailable isoxazoline benzoxaborole (AN8030) as a long acting animal ectoparasiticide.
Zhang, Yong-Kang; Plattner, Jacob J; Easom, Eric E; Zhou, Yasheen; Akama, Tsutomu; Bu, Wei; White, W Hunter; Defauw, Jean M; Winkle, Joseph R; Balko, Terry W; Guo, Shenghai; Xue, Jian; Cao, Jianxin; Zou, Wuxin.
Afiliação
  • Zhang YK; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Plattner JJ; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Easom EE; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Zhou Y; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Akama T; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • Bu W; Anacor Pharmaceuticals, Inc., 1020 E. Meadow Circle, Palo Alto, CA 94303, USA.
  • White WH; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Defauw JM; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Winkle JR; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Balko TW; Elanco Animal Health Research and Development, A Division of Eli Lilly & Company, 2500 Innovation Way, Greenfield, IN 46140, USA.
  • Guo S; Shanghai Medicilon, Inc., 585 Chuanda Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai 201200, China.
  • Xue J; Shanghai Medicilon, Inc., 585 Chuanda Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai 201200, China.
  • Cao J; Shanghai ChemPartner, 998 Halei Road, Zhangjiang High-tech Park, Pudong New Area, Shanghai 201203, China.
  • Zou W; BioDuro LLC, Building E, No. 29, Life Science Park Road, Beijing 102206, China.
Bioorg Med Chem Lett ; 25(23): 5589-93, 2015 Dec 01.
Article em En | MEDLINE | ID: mdl-26508546
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Boro / Doenças do Cão / Ectoparasitoses / Descoberta de Drogas / Isoxazóis Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Compostos de Boro / Doenças do Cão / Ectoparasitoses / Descoberta de Drogas / Isoxazóis Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos