Clinical Impact of ß-Lactamase-producing Enterobacteriaceae in Sputum of Cystic Fibrosis Patients.
Pediatr Infect Dis J
; 35(2): 216-9, 2016 Feb.
Article
em En
| MEDLINE
| ID: mdl-26544988
ABSTRACT
This case series describes 18 cystic fibrosis (CF) patients of a 135-patient CF center cohort with extended spectrum ß-lactamase-producing Enterobacteriaceae, from 2003 to 2012. Four had chronic infection. Prevalence increased annually from 0 to 6.35%. Risk factors compared with the 2010 CF center cohort included continuous inhaled antibiotics (P = 0.014) and courses of intravenous antibiotics during the year before first isolation (P = 0.009). Hospitalization rates were 1.05/year and 0.47/year preinfection and postinfection, respectively (P = 0.02). Slope of forced expiratory volume at 1 second% predicted remained unchanged during 12 months.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Escarro
/
Beta-Lactamases
/
Fibrose Cística
/
Enterobacteriaceae
/
Infecções por Enterobacteriaceae
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Israel