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Directed evolution of the tryptophan synthase ß-subunit for stand-alone function recapitulates allosteric activation.
Buller, Andrew R; Brinkmann-Chen, Sabine; Romney, David K; Herger, Michael; Murciano-Calles, Javier; Arnold, Frances H.
Afiliação
  • Buller AR; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
  • Brinkmann-Chen S; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
  • Romney DK; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
  • Herger M; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
  • Murciano-Calles J; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.
  • Arnold FH; Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125 frances@cheme.caltech.edu.
Proc Natl Acad Sci U S A ; 112(47): 14599-604, 2015 Nov 24.
Article em En | MEDLINE | ID: mdl-26553994
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triptofano Sintase / Evolução Molecular Direcionada / Pyrococcus furiosus / Subunidades Proteicas Idioma: En Ano de publicação: 2015 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triptofano Sintase / Evolução Molecular Direcionada / Pyrococcus furiosus / Subunidades Proteicas Idioma: En Ano de publicação: 2015 Tipo de documento: Article