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Estimation of Drug Binding to Brain Tissue: Methodology and in Vivo Application of a Distribution Assay in Brain Polar Lipids.
Belli, Sara; Assmus, Frauke; Wagner, Bjoern; Honer, Michael; Fischer, Holger; Schuler, Franz; Alvarez-Sánchez, Rubén.
Afiliação
  • Belli S; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel , Basel 4070, Switzerland.
  • Assmus F; Center for Applied Pharmacokinetic Research, Manchester Pharmacy School, University of Manchester , Stopford Building, Oxford Road, M13 9PT Manchester, United Kingdom.
  • Wagner B; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel , Basel 4070, Switzerland.
  • Honer M; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel , Basel 4070, Switzerland.
  • Fischer H; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel , Basel 4070, Switzerland.
  • Schuler F; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel , Basel 4070, Switzerland.
  • Alvarez-Sánchez R; Roche Pharmaceutical Research and Early Development, Pharmaceutical Sciences, Roche Innovation Center Basel , Basel 4070, Switzerland.
Mol Pharm ; 12(12): 4529-41, 2015 Dec 07.
Article em En | MEDLINE | ID: mdl-26560069
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bioensaio / Encéfalo / Fármacos do Sistema Nervoso Central / Lipídeos Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Suíça
Texto completo
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XML
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Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Bioensaio / Encéfalo / Fármacos do Sistema Nervoso Central / Lipídeos Idioma: En Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Suíça