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Structure-Based Identification of Inhibitory Fragments Targeting the p300/CBP-Associated Factor Bromodomain.
Chaikuad, Apirat; Lang, Steffen; Brennan, Paul E; Temperini, Claudia; Fedorov, Oleg; Hollander, Johan; Nachane, Ruta; Abell, Chris; Müller, Susanne; Siegal, Gregg; Knapp, Stefan.
Afiliação
  • Chaikuad A; Nuffield Department of Clinical Medicine, Structural Genomics Consortium and Target Discovery Institute, University of Oxford , Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, U.K.
  • Lang S; Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge CB2 1EW, U.K.
  • Brennan PE; Nuffield Department of Clinical Medicine, Structural Genomics Consortium and Target Discovery Institute, University of Oxford , Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, U.K.
  • Temperini C; Leiden Institute of Chemistry, Leiden University , Einsteinweg 55, 2333 CC Leiden, Netherlands.
  • Fedorov O; Nuffield Department of Clinical Medicine, Structural Genomics Consortium and Target Discovery Institute, University of Oxford , Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, U.K.
  • Hollander J; ZoBio , Einsteinweg 55, 2333 CC Leiden, Netherlands.
  • Nachane R; ZoBio , Einsteinweg 55, 2333 CC Leiden, Netherlands.
  • Abell C; Department of Chemistry, University of Cambridge , Lensfield Road, Cambridge CB2 1EW, U.K.
  • Müller S; Nuffield Department of Clinical Medicine, Structural Genomics Consortium and Target Discovery Institute, University of Oxford , Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, U.K.
  • Siegal G; ZoBio , Einsteinweg 55, 2333 CC Leiden, Netherlands.
  • Knapp S; Nuffield Department of Clinical Medicine, Structural Genomics Consortium and Target Discovery Institute, University of Oxford , Old Road Campus Research Building, Roosevelt Drive, Oxford, OX3 7DQ, U.K.
J Med Chem ; 59(4): 1648-53, 2016 Feb 25.
Article em En | MEDLINE | ID: mdl-26731131
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição de p300-CBP / Bibliotecas de Moléculas Pequenas Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fatores de Transcrição de p300-CBP / Bibliotecas de Moléculas Pequenas Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Reino Unido