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Total Syntheses of (R)-Strongylodiols C and D.
Liu, Feipeng; Zhong, Jiangchun; Li, Shuoning; Li, Minyan; Wu, Lin; Wang, Qian; Mao, Jianyou; Liu, Shikuo; Zheng, Bing; Wang, Min; Bian, Qinghua.
Afiliação
  • Liu F; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Zhong J; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Li S; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Li M; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Wu L; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Wang Q; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Mao J; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Liu S; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Zheng B; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Wang M; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
  • Bian Q; Department of Applied Chemistry, China Agricultural University , 2 West Yuanmingyuan Road, Beijing 100193, People's Republic of China.
J Nat Prod ; 79(1): 244-7, 2016 Jan 22.
Article em En | MEDLINE | ID: mdl-26735019
ABSTRACT
The first total syntheses of two marine natural products, (R)-strongylodiols C and D, with 99% ee were achieved. The key steps of the strategy include the zipper reaction of an alkyne, the asymmetric alkynylation of an unsaturated aliphatic aldehyde catalyzed with Trost's ProPhenol ligand, and the Cadiot-Chodkiewicz cross-coupling reaction of a chiral propargylic alcohol with a bromoalkyne.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Álcoois / Alcinos Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Álcoois / Alcinos Idioma: En Ano de publicação: 2016 Tipo de documento: Article