Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-&#945; via p38 and NF&#954;-B signaling in RAW 264.7 macrophages.

Lee, Kyung Jin; Kim, Yun Kyu; Krupa, Martin; Nguyen, Anh Ngoc; Do, Bich Hang; Chung, Boram; Vu, Thi Thu Trang; Kim, Song Cheol; Choe, Han

Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages.

Lee, Kyung Jin; Kim, Yun Kyu; Krupa, Martin; Nguyen, Anh Ngoc; Do, Bich Hang; Chung, Boram; Vu, Thi Thu Trang; Kim, Song Cheol; Choe, Han.

Afiliação

Lee KJ; Department of Convergence Medicine, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Kim YK; Department of Convergence Medicine, Asan Institute for Life Sciences, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Krupa M; Department of Physiology and Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Nguyen AN; Department of Physiology and Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Do BH; Department of Physiology and Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Chung B; Department of Physiology and Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Vu TT; Department of Physiology and Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Kim SC; Department of Surgery, Division of Hepatobilopancreatic Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.
Choe H; Department of Physiology and Bio-Medical Institute of Technology, University of Ulsan College of Medicine, Asan Medical Center, Seoul 05505, Korea.

BMB Rep ; 49(3): 185-90, 2016 Mar.

Article em En | MEDLINE | ID: mdl-26818089

Assuntos

Venenos de Crotalídeos/farmacologia; Macrófagos/metabolismo; NF-kappa B/metabolismo; Óxido Nítrico/metabolismo; Fagocitose/efeitos dos fármacos; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/metabolismo; Animais; Morte Celular/efeitos dos fármacos; Ativação Enzimática/efeitos dos fármacos; Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos; Macrófagos/efeitos dos fármacos; Macrófagos/enzimologia; Camundongos; Óxido Nítrico Sintase Tipo II/genética; Óxido Nítrico Sintase Tipo II/metabolismo; Fosforilação/efeitos dos fármacos; Células RAW 264.7; RNA Mensageiro/genética; RNA Mensageiro/metabolismo; Ativação Transcricional/efeitos dos fármacos; Fator de Necrose Tumoral alfa/genética; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fagocitose / Transdução de Sinais / NF-kappa B / Fator de Necrose Tumoral alfa / Venenos de Crotalídeos / Macrófagos / Óxido Nítrico Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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