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Massively parallel sequencing of phyllodes tumours of the breast reveals actionable mutations, and TERT promoter hotspot mutations and TERT gene amplification as likely drivers of progression.
Piscuoglio, Salvatore; Ng, Charlotte Ky; Murray, Melissa; Burke, Kathleen A; Edelweiss, Marcia; Geyer, Felipe C; Macedo, Gabriel S; Inagaki, Akiko; Papanastasiou, Anastasios D; Martelotto, Luciano G; Marchio, Caterina; Lim, Raymond S; Ioris, Rafael A; Nahar, Pooja K; Bruijn, Ino De; Smyth, Lillian; Akram, Muzaffar; Ross, Dara; Petrini, John H; Norton, Larry; Solit, David B; Baselga, Jose; Brogi, Edi; Ladanyi, Marc; Weigelt, Britta; Reis-Filho, Jorge S.
Afiliação
  • Piscuoglio S; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Ng CK; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Murray M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Burke KA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Edelweiss M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Geyer FC; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Macedo GS; Department of Pathology, Hospital Israelita Albert Einstein, Instituto Israelita de Ensino e Pesquisa, São Paulo, Brazil.
  • Inagaki A; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Papanastasiou AD; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Martelotto LG; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Marchio C; Department of Pathology, Patras General Hospital, Greece.
  • Lim RS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Ioris RA; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Nahar PK; Department of Medical Sciences, University of Turin, Italy.
  • Bruijn ID; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Smyth L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Akram M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Ross D; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Petrini JH; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Norton L; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Solit DB; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Baselga J; Molecular Biology Program, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Brogi E; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Ladanyi M; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Weigelt B; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, USA.
  • Reis-Filho JS; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, USA.
J Pathol ; 238(4): 508-18, 2016 Mar.
Article em En | MEDLINE | ID: mdl-26832993
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Regiões Promotoras Genéticas / Fibroadenoma / Tumor Filoide / Telomerase / Mutação / Recidiva Local de Neoplasia Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Regiões Promotoras Genéticas / Fibroadenoma / Tumor Filoide / Telomerase / Mutação / Recidiva Local de Neoplasia Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos