Hypoxia Challenge Testing in Neonates for Fitness to Fly.
Pediatrics
; 137(3): e20152915, 2016 Mar.
Article
em En
| MEDLINE
| ID: mdl-26908703
ABSTRACT
BACKGROUND:
Preflight hypoxia challenge testing (HCT) in a body plethysmograph has previously been done only on infants >3 months of corrected gestational age (CGA). This study aims to determine the earliest fit-to-fly age by testing neonates <1 week old.METHODS:
A prospective observational study was carried out on 3 groups of infants healthy term infants ≤7 days old, preterm infants (≥34 weeks CGA) 2 to 3 days before discharge, and preterm infants with bronchopulmonary dysplasia (BPD). HCT was conducted using a body plethysmograph with a 15% fraction of inspired oxygen. The oxygen saturation (Spo2) test fail point was <85%.RESULTS:
Twenty-four term (mean CGA 40 weeks), 62 preterm (37 weeks), and 23 preterm with BPD (39.5 weeks) infants were tested. One term infant (4.2%) and 12 preterm infants without BPD (19.4%) failed. Sixteen (69.3%) preterm infants with BPD failed (P < .001), with a median drop in Spo2 of 16%. At 39 weeks CGA, neither preterm infants without BPD nor term infants had an Spo2 <85%. However, 7 of 12 term infants with BPD failed the HCT.CONCLUSIONS:
Term and preterm infants without BPD born at >39 weeks CGA do not appear to be likely to desaturate during a preflight HCT and so can be deemed fit to fly according to current British Thoracic Society Guidelines.
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Base de dados:
MEDLINE
Assunto principal:
Viagem
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Recém-Nascido Prematuro
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Medicina Aeroespacial
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Fenômenos Fisiológicos da Nutrição do Lactente
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Doenças do Prematuro
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Hipóxia
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article