Atomic resolution probe for allostery in the regulatory thin filament.

Williams, Michael R; Lehman, Sarah J; Tardiff, Jil C; Schwartz, Steven D

Williams, Michael R; Lehman, Sarah J; Tardiff, Jil C; Schwartz, Steven D.

Afiliação

Williams MR; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, AZ 85721;
Lehman SJ; Physiological Sciences, The University of Arizona, Tucson, AZ 85724;
Tardiff JC; Department of Medicine, The University of Arizona, Tucson, AZ 85724; Department of Cellular and Molecular Medicine, The University of Arizona, Tucson, AZ 85724.
Schwartz SD; Department of Chemistry and Biochemistry, The University of Arizona, Tucson, AZ 85721; sschwartz@email.arizona.edu.

Proc Natl Acad Sci U S A ; 113(12): 3257-62, 2016 Mar 22.

Article em En | MEDLINE | ID: mdl-26957598

Assuntos

Troponina T/metabolismo; Regulação Alostérica; Cálcio/metabolismo; Humanos; Modelos Químicos; Troponina T/química

Palavras-chave

calcium homeostasis; cardiac thin filament; hypertrophic cardiomyopathy; molecular modeling; steered molecular dynamics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Troponina T Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Troponina T Idioma: En Ano de publicação: 2016 Tipo de documento: Article