[Chemical Constituents from Angelica keiskei].

ABSTRACT

OBJECTIVE: To investigate the chemical constituents from Angelica keiskei. METHODS: The constituents were isolated and purified by silica gel, Sephadex LH-20 column chromatography, and preparative TLC. Their structures were identified on the basis of spectral data and physiochemical characteristics. RESULTS: 14 compounds were isolated from 70% ethanol extracts and identified as falcarindiol (1), selinidin (2), isobavachalcone (3), pteryxin (4), kaempferol-5-O-(6"-O-acetyl)-ß-D-glucopyranoside (5), ß-amyrin ace- tate (6), ß-sitosteryl glucoside-6'-O-heptadecoicate (7), 2,5-dimethyl-6,8-dihydroxyl-chromone (8), quercetin-3,3'-di-O-α-L-rhamno- side (9), 2-hydroxynaringenin-4'-O-glucopyranoside (10), 3-O-α-L-rhamnosyl (1-->3)-ß-D-glucopyranosyl (1-->3)-α-L-rhamnosyl (1--> 2)-α-L-arabinopyranosyl hederagenin-28-O-ß-D-glucopyranosyl (1-->6)-ß-D-glucopyranosyl ester (11), chrysoeriol (12), orientin (13) and 1ß,6α-dihydroxyeudesm-4 (15)-ene (14). CONCLUSION: All compounds are isolated from this plant for the first time.