Design, synthesis, and evaluation of hinge-binder tethered 1,2,3-triazolylsalicylamide derivatives as Aurora kinase inhibitors.

Jeong, Yunkyung; Lee, Jooyeon; Ryu, Jae-Sang

Jeong, Yunkyung; Lee, Jooyeon; Ryu, Jae-Sang.

Afiliação

Jeong Y; College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea.
Lee J; College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea.
Ryu JS; College of Pharmacy & Graduate School of Pharmaceutical Sciences, Ewha Womans University, 52 Ewhayeodae-gil, Seodaemun-gu, Seoul 03760, Republic of Korea. Electronic address: ryuj@ewha.ac.kr.

Bioorg Med Chem ; 24(9): 2114-24, 2016 May 01.

Article em En | MEDLINE | ID: mdl-27041399

Assuntos

Aurora Quinase A/antagonistas & inibidores; Inibidores de Proteínas Quinases/farmacologia; Salicilamidas/farmacologia

Palavras-chave

1,2,3-Triazole; Anticancer; Aurora kinase; Click chemistry; Hinge-binder

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Salicilamidas / Inibidores de Proteínas Quinases / Aurora Quinase A Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google