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Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR.
Heffron, Timothy P; Ndubaku, Chudi O; Salphati, Laurent; Alicke, Bruno; Cheong, Jonathan; Drobnick, Joy; Edgar, Kyle; Gould, Stephen E; Lee, Leslie B; Lesnick, John D; Lewis, Cristina; Nonomiya, Jim; Pang, Jodie; Plise, Emile G; Sideris, Steve; Wallin, Jeffrey; Wang, Lan; Zhang, Xiaolin; Olivero, Alan G.
Afiliação
  • Heffron TP; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Ndubaku CO; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Salphati L; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Alicke B; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Cheong J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Drobnick J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Edgar K; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Gould SE; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Lee LB; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Lesnick JD; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Lewis C; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Nonomiya J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Pang J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Plise EG; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Sideris S; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wallin J; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Wang L; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Zhang X; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
  • Olivero AG; Genentech, Inc. , 1 DNA Way, South San Francisco, California 94080, United States.
ACS Med Chem Lett ; 7(4): 351-6, 2016 Apr 14.
Article em En | MEDLINE | ID: mdl-27096040
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Estados Unidos