Determining jitter values in the very young by use of the e-norms methodology.
Muscle Nerve
; 55(1): 51-54, 2017 01.
Article
em En
| MEDLINE
| ID: mdl-27184476
ABSTRACT
INTRODUCTION:
The diagnosis of myasthenia gravis in very young infants is a challenging one. In young infants, stimulated single-fiber electromyography (StimSFEMG) is the most appropriate technique, but it has serious limitations due to the absence of reference values in this subpopulation. Here we present our efforts to derive a reference range of jitter in a patient cohort of infants <3 years of age using the extrapolated norms, or e-norms, technique.METHODS:
The e-norms method was used to calculate jitter mean consecutive difference (MCD) descriptive statistics for children <3 years of age.RESULTS:
The e-norms derived jitter upper MCD limit was 45 µs in children <1 year, 33 µs in those <2 years, and 26 in those <3 years of age.CONCLUSION:
In the absence of jitter reference values for the very young, the e-norms method can be used as an alternative to derive these values from laboratory cohorts. Muscle Nerve 55 51-54, 2017.Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Fibras Musculares Esqueléticas
/
Contração Muscular
/
Miastenia Gravis
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Reino Unido