Comparative Proteomics Reveals Dysregulated Mitochondrial O-GlcNAcylation in Diabetic Hearts.

Ma, Junfeng; Banerjee, Partha; Whelan, Stephen A; Liu, Ting; Wei, An-Chi; Ramirez-Correa, Genaro; McComb, Mark E; Costello, Catherine E; O'Rourke, Brian; Murphy, Anne; Hart, Gerald W

Ma, Junfeng; Banerjee, Partha; Whelan, Stephen A; Liu, Ting; Wei, An-Chi; Ramirez-Correa, Genaro; McComb, Mark E; Costello, Catherine E; O'Rourke, Brian; Murphy, Anne; Hart, Gerald W.

Afiliação

Whelan SA; Department of Biochemistry, Boston University School of Medicine , Boston, Massachusetts 02118, United States.
McComb ME; Department of Biochemistry, Boston University School of Medicine , Boston, Massachusetts 02118, United States.
Costello CE; Department of Biochemistry, Boston University School of Medicine , Boston, Massachusetts 02118, United States.

J Proteome Res ; 15(7): 2254-64, 2016 07 01.

Article em En | MEDLINE | ID: mdl-27213235

Assuntos

Acetilglucosamina/metabolismo; Cardiomiopatias Diabéticas/metabolismo; Proteínas Mitocondriais/metabolismo; Proteômica/métodos; Acilação; Animais; Diabetes Mellitus Experimental; Mitocôndrias/metabolismo; Proteínas Mitocondriais/análise; Miocárdio/metabolismo; Ratos; Espectrometria de Massas em Tandem

Palavras-chave

O-GlcNAcome; O-GlcNAcylation; diabetic cardiomyopathy; mass spectrometry; mitochondria; proteomics; pyruvate dehydrogenase

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Acetilglucosamina / Proteínas Mitocondriais / Proteômica / Cardiomiopatias Diabéticas Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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