Gestational and Early Postnatal Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants: General Toxicity and Skeletal Variations.

Tung, Emily W Y; Yan, Han; Lefèvre, Pavine L C; Berger, Robert G; Rawn, Dorothea F K; Gaertner, Dean W; Kawata, Alice; Rigden, Marc; Robaire, Bernard; Hales, Barbara F; Wade, Michael G

Tung, Emily W Y; Yan, Han; Lefèvre, Pavine L C; Berger, Robert G; Rawn, Dorothea F K; Gaertner, Dean W; Kawata, Alice; Rigden, Marc; Robaire, Bernard; Hales, Barbara F; Wade, Michael G.

Afiliação

Tung EW; Environmental Health Science & Research Bureau, Health Canada, Ottawa, Ontario, Canada.
Yan H; Department of Pharmacology and Therapeutics, McGill University, Montréal, Quebec, Canada.
Lefèvre PL; Department of Pharmacology and Therapeutics, McGill University, Montréal, Quebec, Canada.
Berger RG; Department of Pharmacology and Therapeutics, McGill University, Montréal, Quebec, Canada.
Rawn DF; Food Research Division, Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.
Gaertner DW; Food Research Division, Bureau of Chemical Safety, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.
Kawata A; Environmental Health Science & Research Bureau, Health Canada, Ottawa, Ontario, Canada.
Rigden M; Environmental Health Science & Research Bureau, Health Canada, Ottawa, Ontario, Canada.
Robaire B; Department of Pharmacology and Therapeutics, McGill University, Montréal, Quebec, Canada.
Hales BF; Department of Obstetrics and Gynecology, McGill University, Montréal, Quebec, Canada.
Wade MG; Department of Pharmacology and Therapeutics, McGill University, Montréal, Quebec, Canada.

Birth Defects Res B Dev Reprod Toxicol ; 107(3): 157-68, 2016 Jun.

Article em En | MEDLINE | ID: mdl-27286044

Assuntos

Desenvolvimento Ósseo/efeitos dos fármacos; Osso e Ossos/efeitos dos fármacos; Retardadores de Chama/toxicidade; Éteres Difenil Halogenados/toxicidade; Exposição Materna/efeitos adversos; Alanina Transaminase/sangue; Fosfatase Alcalina/sangue; Animais; Aspartato Aminotransferases/sangue; Biomarcadores/sangue; Peso Corporal; Osso e Ossos/patologia; Creatina Quinase/sangue; Creatinina/sangue; Modelos Animais de Doenças; Relação Dose-Resposta a Droga; Feminino; Hidrocarbonetos Bromados/toxicidade; Fígado/efeitos dos fármacos; Fígado/metabolismo; Tamanho do Órgão/efeitos dos fármacos; Ratos; Ratos Sprague-Dawley; Reprodução/efeitos dos fármacos; Albumina Sérica/metabolismo

Palavras-chave

brominated flame retardants; hexabromocyclododecane; polybrominated diphenyl ethers

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Osso e Ossos / Desenvolvimento Ósseo / Exposição Materna / Éteres Difenil Halogenados / Retardadores de Chama Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Canadá

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