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Inhibitors of the Cysteine Synthase CysM with Antibacterial Potency against Dormant Mycobacterium tuberculosis.
Brunner, Katharina; Maric, Selma; Reshma, Rudraraju Srilakshmi; Almqvist, Helena; Seashore-Ludlow, Brinton; Gustavsson, Anna-Lena; Poyraz, Ömer; Yogeeswari, Perumal; Lundbäck, Thomas; Vallin, Michaela; Sriram, Dharmarajan; Schnell, Robert; Schneider, Gunter.
Afiliação
  • Brunner K; Division of Molecular Structural Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 77 Stockholm, Sweden.
  • Maric S; Division of Molecular Structural Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 77 Stockholm, Sweden.
  • Reshma RS; Drug Discovery Research Laboratory, Department of Pharmacy, Birla Institute of Technology & Science-Pilani , Hyderabad Campus, Shameerpet, R.R. District, Hyderabad 500078, Andhra Pradesh India.
  • Almqvist H; Chemical Biology Consortium Sweden, Science for Life Laboratory, Division of Translational Medicine & Chemical Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 65 Solna, Sweden.
  • Seashore-Ludlow B; Chemical Biology Consortium Sweden, Science for Life Laboratory, Division of Translational Medicine & Chemical Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 65 Solna, Sweden.
  • Gustavsson AL; Chemical Biology Consortium Sweden, Science for Life Laboratory, Division of Translational Medicine & Chemical Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 65 Solna, Sweden.
  • Poyraz Ö; Division of Molecular Structural Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 77 Stockholm, Sweden.
  • Yogeeswari P; Drug Discovery Research Laboratory, Department of Pharmacy, Birla Institute of Technology & Science-Pilani , Hyderabad Campus, Shameerpet, R.R. District, Hyderabad 500078, Andhra Pradesh India.
  • Lundbäck T; Chemical Biology Consortium Sweden, Science for Life Laboratory, Division of Translational Medicine & Chemical Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 65 Solna, Sweden.
  • Vallin M; Chemical Biology Consortium Sweden, Science for Life Laboratory, Division of Translational Medicine & Chemical Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 65 Solna, Sweden.
  • Sriram D; Drug Discovery Research Laboratory, Department of Pharmacy, Birla Institute of Technology & Science-Pilani , Hyderabad Campus, Shameerpet, R.R. District, Hyderabad 500078, Andhra Pradesh India.
  • Schnell R; Division of Molecular Structural Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 77 Stockholm, Sweden.
  • Schneider G; Division of Molecular Structural Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet , S-171 77 Stockholm, Sweden.
J Med Chem ; 59(14): 6848-59, 2016 07 28.
Article em En | MEDLINE | ID: mdl-27379713
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína Sintase / Inibidores Enzimáticos / Antibacterianos / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suécia
Texto completo
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XML
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Cisteína Sintase / Inibidores Enzimáticos / Antibacterianos / Mycobacterium tuberculosis Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: Suécia