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The structural basis of the dominant negative phenotype of the Gαi1ß1γ2 G203A/A326S heterotrimer.
Liu, Ping; Jia, Ming-Zhu; Zhou, X Edward; De Waal, Parker W; Dickson, Bradley M; Liu, Bo; Hou, Li; Yin, Yan-Ting; Kang, Yan-Yong; Shi, Yi; Melcher, Karsten; Xu, H Eric; Jiang, Yi.
Afiliação
  • Liu P; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Jia MZ; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Zhou XE; Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
  • De Waal PW; Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
  • Dickson BM; Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
  • Liu B; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Hou L; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Yin YT; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Kang YY; Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
  • Shi Y; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Melcher K; Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
  • Xu HE; VARI-SIMM Center, Center for Structure and Function of Drug Targets, CAS-Key Laboratory of Receptor Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.
  • Jiang Y; Laboratory of Structural Sciences, Van Andel Research Institute, Grand Rapids, MI 49503, USA.
Acta Pharmacol Sin ; 37(9): 1259-72, 2016 Sep.
Article em En | MEDLINE | ID: mdl-27498775
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP / Subunidades beta da Proteína de Ligação ao GTP / Subunidades gama da Proteína de Ligação ao GTP Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP / Subunidades beta da Proteína de Ligação ao GTP / Subunidades gama da Proteína de Ligação ao GTP Idioma: En Ano de publicação: 2016 Tipo de documento: Article País de afiliação: China