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Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma.
Reinartz, Roman; Wang, Shanshan; Kebir, Sied; Silver, Daniel J; Wieland, Anja; Zheng, Tong; Küpper, Marius; Rauschenbach, Laurèl; Fimmers, Rolf; Shepherd, Timothy M; Trageser, Daniel; Till, Andreas; Schäfer, Niklas; Glas, Martin; Hillmer, Axel M; Cichon, Sven; Smith, Amy A; Pietsch, Torsten; Liu, Ying; Reynolds, Brent A; Yachnis, Anthony; Pincus, David W; Simon, Matthias; Brüstle, Oliver; Steindler, Dennis A; Scheffler, Björn.
Afiliação
  • Reinartz R; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Wang S; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Kebir S; Department of Neurosurgery, University of Florida, Gainesville, Florida.
  • Silver DJ; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Wieland A; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Zheng T; Department of Cellular & Molecular Medicine, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio.
  • Küpper M; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Rauschenbach L; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Fimmers R; Department of Neurosurgery, University of Florida, Gainesville, Florida.
  • Shepherd TM; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Trageser D; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Till A; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Schäfer N; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Glas M; Institute for Medical Biometry, Informatics & Epidemiology, University of Bonn, Bonn, Germany.
  • Hillmer AM; Department of Neuroradiology, NYU Langone Medical Center, New York, New York.
  • Cichon S; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Smith AA; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Pietsch T; LIFE & BRAIN GmbH, Bonn, Germany.
  • Liu Y; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Reynolds BA; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Yachnis A; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Pincus DW; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Simon M; Stem Cell Pathologies, University of Bonn Medical Center, Bonn, Germany.
  • Brüstle O; Institute of Reconstructive Neurobiology, University of Bonn Medical Center, Bonn, Germany.
  • Steindler DA; LIFE & BRAIN GmbH, Bonn, Germany.
  • Scheffler B; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore.
Clin Cancer Res ; 23(2): 562-574, 2017 Jan 15.
Article em En | MEDLINE | ID: mdl-27521447

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Heterogeneidade Genética / Resistencia a Medicamentos Antineoplásicos / Combinação de Medicamentos Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glioblastoma / Heterogeneidade Genética / Resistencia a Medicamentos Antineoplásicos / Combinação de Medicamentos Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Alemanha