Long-term effects of high-intensity interval training in heart transplant recipients: A 5-year follow-up study of a randomized controlled trial.
Clin Transplant
; 31(1)2017 01.
Article
em En
| MEDLINE
| ID: mdl-27865004
ABSTRACT
BACKGROUND:
Previous studies have demonstrated that high-intensity interval training (HIT) is superior to moderate-continuous exercise in general and in cardiovascular diseases. Recently, we also found HIT safe and efficient after heart transplantation (HTx). This study reports the 5-year long-term effects. DESIGN ANDMETHODS:
Forty-one HTx patients who had completed the previous 12-month randomized controlled trial, comparing HIT intervention with usual care, were eligible. In particular, we measured VO2peak , muscular capacity, intravascular ultrasound, and questionnaires measuring physical and mental health.RESULTS:
The baseline mean±SD values were as follows age; 49.1±16.5 years, men; 68%, time since HTx 4.1±2.2 years. Within the HIT group, initial VO2peak increased significantly from 27.7±5.7 to 31.2±5.3 mL/kg/min. However, during the next 4 years, VO2peak decreased to 26.0±6.2 mL/kg/min. The control group showed slightly decreasing VO2peak values during the entire 5-year period. The HIT group reported significantly less anxiety symptoms, but there were no long-term differences in VO2peak , muscular capacity, or cardiac allograft vasculopathy between the groups. The similar VO2peak values correspond to our findings of similar everyday activity.CONCLUSION:
Our findings suggest that intermittent periods of HIT may be necessary to maintain the initial benefits gained from the intervention. However, HIT probably reduces the burden of anxiety, which is a frequent health issue following HTx.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Exercício Físico
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Transplante de Coração
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Transplantados
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Treinamento Intervalado de Alta Intensidade
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Cardiopatias
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Noruega