A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity.

Lok, Hiu Chuen; Sahni, Sumit; Jansson, Patric J; Kovacevic, Zaklina; Hawkins, Clare L; Richardson, Des R

Lok, Hiu Chuen; Sahni, Sumit; Jansson, Patric J; Kovacevic, Zaklina; Hawkins, Clare L; Richardson, Des R.

Afiliação

Lok HC; From the Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006 and.
Sahni S; From the Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006 and.
Jansson PJ; From the Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006 and.
Kovacevic Z; From the Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006 and.
Hawkins CL; the Heart Research Institute, Sydney, New South Wales 2042, Australia.
Richardson DR; From the Molecular Pharmacology and Pathology Program, Department of Pathology and Bosch Institute, University of Sydney, Sydney, New South Wales 2006 and d.richardson@med.usyd.edu.au.

J Biol Chem ; 291(53): 27042-27061, 2016 12 30.

Article em En | MEDLINE | ID: mdl-27866158

Assuntos

Glutationa S-Transferase pi/antagonistas & inibidores; Isótopos de Ferro/metabolismo; Ativação de Macrófagos/efeitos dos fármacos; Macrófagos/efeitos dos fármacos; Proteínas Associadas à Resistência a Múltiplos Medicamentos/antagonistas & inibidores; Óxido Nítrico/metabolismo; Animais; Transporte Biológico; Broncodilatadores/farmacologia; Células Cultivadas; Glutationa/metabolismo; Glutationa S-Transferase pi/fisiologia; Macrófagos/metabolismo; Macrófagos/patologia; Camundongos; Camundongos Knockout; Proteínas Associadas à Resistência a Múltiplos Medicamentos/fisiologia; Óxido Nítrico/toxicidade; Propionatos/farmacologia; Substâncias Protetoras/farmacologia; Quinolinas/farmacologia; RNA Interferente Pequeno/genética

Palavras-chave

electron paramagnetic resonance (EPR); macrophage; nitric oxide; nitric oxide synthase; tumor

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Associadas à Resistência a Múltiplos Medicamentos / Glutationa S-Transferase pi / Isótopos de Ferro / Ativação de Macrófagos / Macrófagos / Óxido Nítrico Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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