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In Vitro and in Silico Tools To Assess Extent of Cellular Uptake and Lysosomal Sequestration of Respiratory Drugs in Human Alveolar Macrophages.
Ufuk, Ayse; Assmus, Frauke; Francis, Laura; Plumb, Jonathan; Damian, Valeriu; Gertz, Michael; Houston, J Brian; Galetin, Aleksandra.
Afiliação
  • Ufuk A; Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester , Manchester, U.K.
  • Assmus F; Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester , Manchester, U.K.
  • Francis L; Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester , Manchester, U.K.
  • Plumb J; Respiratory and Allergy Clinical Research Facility, University Hospital of South Manchester , Manchester, U.K.
  • Damian V; Computational Modeling Sciences, DDS, GlaxoSmithKline , Upper Merion, Pennsylvania 19406, United States.
  • Gertz M; Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester , Manchester, U.K.
  • Houston JB; Pharmaceutical Sciences, pRED, Roche Innovation Center , Basel, Switzerland.
  • Galetin A; Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester , Manchester, U.K.
Mol Pharm ; 14(4): 1033-1046, 2017 04 03.
Article em En | MEDLINE | ID: mdl-28252969
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Macrófagos Alveolares / Lisossomos Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Preparações Farmacêuticas / Macrófagos Alveolares / Lisossomos Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido