[Pulmonary metastasectomy in renal cell carcinoma]. / Lungenmetastasenchirurgie beim Nierenzellkarzinom.
Urologe A
; 56(8): 1025-1030, 2017 Aug.
Article
em De
| MEDLINE
| ID: mdl-28280862
ABSTRACT
BACKGROUND:
In patients with isolated meta- or synchronous pulmonary metastases from renal cell cancer, lung metastasectomy could be an appropriate treatment option after successful treatment of primary cancer.OBJECTIVES:
Presentation of lung metastasectomy as a treatment option in patients with pulmonary metastatic renal cell cancer and the postoperative outcome. Description of alternative treatment modalities focusing on "targeted therapies". MATERIALS ANDMETHODS:
Systematical literature research and qualitative analysis of studies on patients undergoing lung metastasectomy after primary nephrectomy published since 01 January 2000. We assessed operative findings, survival data, and prognostic factors.RESULTS:
Pulmonary metastasectomy results in a median postmetastasectomy survival of 26-94 months. The 5year survival rates vary between 33 and 58%. The patients' prognosis depends on a prolonged disease-free interval and complete resection of all suspected metastases. In particular, number and location of lung metastases should play a minor role for the indication for lung metastasectomy.CONCLUSIONS:
Pulmonary metastasectomy should be considered the treatment of choice in selected patients with successfully resected primary cancer showing no evidence of extrapulmonary metastases and having guaranteed operability and complete resection.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Carcinoma de Células Renais
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Metastasectomia
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Neoplasias Renais
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Neoplasias Pulmonares
Idioma:
De
Ano de publicação:
2017
Tipo de documento:
Article