Capacity of Pneumococci to Activate Macrophage Nuclear Factor &#954;B: Influence on Necroptosis and Pneumonia Severity.

Coleman, Fadie T; Blahna, Matthew T; Kamata, Hirofumi; Yamamoto, Kazuko; Zabinski, Mary C; Kramnik, Igor; Wilson, Andrew A; Kotton, Darrell N; Quinton, Lee J; Jones, Matthew R; Pelton, Stephen I; Mizgerd, Joseph P

Capacity of Pneumococci to Activate Macrophage Nuclear Factor κB: Influence on Necroptosis and Pneumonia Severity.

Coleman, Fadie T; Blahna, Matthew T; Kamata, Hirofumi; Yamamoto, Kazuko; Zabinski, Mary C; Kramnik, Igor; Wilson, Andrew A; Kotton, Darrell N; Quinton, Lee J; Jones, Matthew R; Pelton, Stephen I; Mizgerd, Joseph P.

Afiliação

Coleman FT; Pulmonary Center.
Blahna MT; Department of Microbiology.
Kamata H; Pulmonary Center.
Yamamoto K; Pulmonary Center.
Zabinski MC; Pulmonary Center.
Kramnik I; Pulmonary Center.
Wilson AA; Pulmonary Center.
Kotton DN; Department of Microbiology.
Quinton LJ; Deparment of Medicine.
Jones MR; Pulmonary Center.
Pelton SI; Deparment of Medicine.
Mizgerd JP; Pulmonary Center.

J Infect Dis ; 216(4): 425-435, 2017 08 15.

Article em En | MEDLINE | ID: mdl-28368460

Assuntos

Macrófagos Alveolares/metabolismo; NF-kappa B/metabolismo; Necrose/imunologia; Pneumonia Pneumocócica/imunologia; Streptococcus pneumoniae; Animais; Modelos Animais de Doenças; Feminino; Imunidade Inata; Macrófagos Alveolares/microbiologia; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Necrose/terapia; Pneumonia Pneumocócica/terapia; Células RAW 264.7; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

NF-κB; community-acquired pneumonia; innate immunity; macrophages; pneumococcus

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pneumonia Pneumocócica / Streptococcus pneumoniae / NF-kappa B / Macrófagos Alveolares / Necrose Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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