CD151 supports VCAM-1-mediated lymphocyte adhesion to liver endothelium and is upregulated in chronic liver disease and hepatocellular carcinoma.

Wadkin, James C R; Patten, Daniel A; Kamarajah, Sivesh K; Shepherd, Emma L; Novitskaya, Vera; Berditchevski, Fedor; Adams, David H; Weston, Chris J; Shetty, Shishir

Wadkin, James C R; Patten, Daniel A; Kamarajah, Sivesh K; Shepherd, Emma L; Novitskaya, Vera; Berditchevski, Fedor; Adams, David H; Weston, Chris J; Shetty, Shishir.

Afiliação

Wadkin JCR; Birmingham Liver Biomedical Research Unit Institute of Immunology and Immunotherapy, National Institute for Health Research, University of Birmingham, Birmingham, United Kingdom.
Patten DA; Birmingham Liver Biomedical Research Unit Institute of Immunology and Immunotherapy, National Institute for Health Research, University of Birmingham, Birmingham, United Kingdom.
Kamarajah SK; Birmingham Liver Biomedical Research Unit Institute of Immunology and Immunotherapy, National Institute for Health Research, University of Birmingham, Birmingham, United Kingdom.
Shepherd EL; Birmingham Liver Biomedical Research Unit Institute of Immunology and Immunotherapy, National Institute for Health Research, University of Birmingham, Birmingham, United Kingdom.
Novitskaya V; CRUK Institute for Cancer Studies, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; and.
Berditchevski F; CRUK Institute for Cancer Studies, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom; and.
Adams DH; Birmingham Liver Biomedical Research Unit Institute of Immunology and Immunotherapy, National Institute for Health Research, University of Birmingham, Birmingham, United Kingdom.
Weston CJ; Liver Unit, University Hospitals Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, United Kingdom.
Shetty S; Birmingham Liver Biomedical Research Unit Institute of Immunology and Immunotherapy, National Institute for Health Research, University of Birmingham, Birmingham, United Kingdom.

Am J Physiol Gastrointest Liver Physiol ; 313(2): G138-G149, 2017 Aug 01.

Article em En | MEDLINE | ID: mdl-28473332

Assuntos

Carcinoma Hepatocelular/metabolismo; Adesão Celular/fisiologia; Doença Hepática Terminal/metabolismo; Neoplasias Hepáticas/metabolismo; Fígado/metabolismo; Linfócitos/metabolismo; Tetraspanina 24/metabolismo; Molécula 1 de Adesão de Célula Vascular/metabolismo; Carcinoma Hepatocelular/patologia; Doença Hepática Terminal/patologia; Humanos; Fígado/efeitos dos fármacos; Fígado/patologia; Neoplasias Hepáticas/patologia; Linfócitos/efeitos dos fármacos; Linfócitos/patologia; Regulação para Cima/efeitos dos fármacos; Fator A de Crescimento do Endotélio Vascular/farmacologia

Palavras-chave

hepatic sinusoidal endothelial cells; lymphocyte recruitment; tetraspanin 24

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos / Adesão Celular / Carcinoma Hepatocelular / Molécula 1 de Adesão de Célula Vascular / Doença Hepática Terminal / Tetraspanina 24 / Fígado / Neoplasias Hepáticas Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Reino Unido

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