Different roles of ß-arrestin and the PKA pathway in mitochondrial ROS production induced by acute ß-adrenergic receptor stimulation in neonatal mouse cardiomyocytes.

Zhang, Jianshu; Xiao, Han; Shen, Jing; Wang, Nanping; Zhang, Youyi

Zhang, Jianshu; Xiao, Han; Shen, Jing; Wang, Nanping; Zhang, Youyi.

Afiliação

Zhang J; Institute of Cardiovascular Sciences, Peking University Health Science Center, No. 38 Xuyuan Road, Beijing, 100191, China. Electronic address: zjs757654065@163.com.
Xiao H; Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Beijing Key Laboratory of Cardiovascular Receptors Research, No. 49 Huanyuanbei Road, Beijing, 100191, China. Electronic address: xiaohan@
Shen J; Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Beijing Key Laboratory of Cardiovascular Receptors Research, No. 49 Huanyuanbei Road, Beijing, 100191, China. Electronic address: sj152230
Wang N; Institute of Cardiovascular Sciences, Peking University Health Science Center, No. 38 Xuyuan Road, Beijing, 100191, China. Electronic address: nanpingwang2003@yahoo.com.
Zhang Y; Institute of Cardiovascular Sciences, Peking University Health Science Center, No. 38 Xuyuan Road, Beijing, 100191, China; Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Cardiovascular Molecular Biology and Regulatory Peptides, Ministry of Health, Beijing Key Lab

Biochem Biophys Res Commun ; 489(4): 393-398, 2017 08 05.

Article em En | MEDLINE | ID: mdl-28552530

Assuntos

Proteínas Quinases Dependentes de AMP Cíclico/metabolismo; Mitocôndrias/metabolismo; Miócitos Cardíacos/metabolismo; Espécies Reativas de Oxigênio/metabolismo; Receptores Adrenérgicos beta/metabolismo; beta-Arrestinas/metabolismo; Agonistas Adrenérgicos beta/farmacologia; Amidas/farmacologia; Animais; Células Cultivadas; Proteínas Quinases Dependentes de AMP Cíclico/antagonistas & inibidores; Camundongos; Camundongos Endogâmicos C57BL; Mitocôndrias/efeitos dos fármacos; Miócitos Cardíacos/efeitos dos fármacos

Palavras-chave

Adrenergic receptors; Cardiomyocytes; Forskolin (PubChem CID: 47936); H-89 dihydrochloride (PubChem CID: 449241); Isoproterenol (PubChem CID: 3779); PKA inhibitor 622 amide (PubChem CID: 71433628); Reactive oxygen species; Rp-adenosine 3',5'-cyclic monophosphorothioate triethylammonium salt (PubChem CID: 16760256); ß-arrestin1

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptores Adrenérgicos beta / Espécies Reativas de Oxigênio / Proteínas Quinases Dependentes de AMP Cíclico / Miócitos Cardíacos / Beta-Arrestinas / Mitocôndrias Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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