Atypical Chronic Myeloid Leukemia, BCR-ABL1 Negative, in a 5-Month Baby - ARare Presentation.
J Coll Physicians Surg Pak
; 26(11): 103-105, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-28666496
ABSTRACT
Atypical chronic myeloid leukemia (aCML) is a neoplasm with poor prognosis, characterized by myeloid hyperplasia, dysmyelopoiesis and absence of BCR-ABL1 gene. Clinically, the disease course may be similar to chronic myeloid leukemia (CML), BCR-ABL1 positive. It presents in seventh to eighth decade of life with few cases of paediatric aCML being reported. Here, we report a case of aCMLin a 5-month baby who presented with massive splenomegaly. The diagnosis was in accordance with the WHO criteria established in 2008.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Leucemia Mieloide Crônica Atípica BCR-ABL Negativa
/
Hidroxiureia
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Antineoplásicos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article