Nano-sized drug carriers: Extravasation, intratumoral distribution, and their modeling.

Nichols, Joseph W; Sakurai, Yu; Harashima, Hideyoshi; Bae, You Han

Nichols, Joseph W; Sakurai, Yu; Harashima, Hideyoshi; Bae, You Han.

Afiliação

Nichols JW; Department of Bioengineering, College of Engineering, University of Utah, 30 S 2000 E, Salt Lake City, Utah 84112, United States.
Sakurai Y; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
Harashima H; Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12, Nishi-6, Kita-ku, Sapporo 060-0812, Japan.
Bae YH; Department of Pharmaceutics and Pharmaceutical Chemistry, College of Pharmacy, University of Utah, 30 S 2000 E, Salt Lake City, Utah 84112, United States. Electronic address: you.bae@utah.edu.

J Control Release ; 267: 31-46, 2017 Dec 10.

Article em En | MEDLINE | ID: mdl-28807683

Assuntos

Portadores de Fármacos/administração & dosagem; Portadores de Fármacos/farmacocinética; Nanopartículas/administração & dosagem; Neoplasias/tratamento farmacológico; Neoplasias/metabolismo; Animais; Portadores de Fármacos/uso terapêutico; Humanos; Modelos Biológicos; Nanopartículas/uso terapêutico

Palavras-chave

Extravasation; Intratumoral distribution; Nanoparticle delivery; Predictive power; Solid tumors; Tumor models

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Portadores de Fármacos / Nanopartículas / Neoplasias Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos

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