Erlotinib attenuates the progression of chronic kidney disease in rats with remnant kidney.

Yamamoto, Yasutaka; Iyoda, Masayuki; Tachibana, Shohei; Matsumoto, Kei; Wada, Yukihiro; Suzuki, Taihei; Iseri, Ken; Saito, Tomohiro; Fukuda-Hihara, Kei; Shibata, Takanori

Yamamoto, Yasutaka; Iyoda, Masayuki; Tachibana, Shohei; Matsumoto, Kei; Wada, Yukihiro; Suzuki, Taihei; Iseri, Ken; Saito, Tomohiro; Fukuda-Hihara, Kei; Shibata, Takanori.

Afiliação

Yamamoto Y; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Iyoda M; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Tachibana S; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Matsumoto K; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Wada Y; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Suzuki T; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Iseri K; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Saito T; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Fukuda-Hihara K; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.
Shibata T; Division of Nephrology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan.

Nephrol Dial Transplant ; 33(4): 598-606, 2018 04 01.

Article em En | MEDLINE | ID: mdl-28992288

Assuntos

Cloridrato de Erlotinib/farmacologia; Fibrose/prevenção & controle; Inibidores de Proteínas Quinases/farmacologia; Insuficiência Renal Crônica/prevenção & controle; Transdução de Sinais/efeitos dos fármacos; Animais; Células Cultivadas; Progressão da Doença; Receptores ErbB/antagonistas & inibidores; Fibrose/etiologia; Fibrose/metabolismo; Humanos; Macrófagos/citologia; Macrófagos/efeitos dos fármacos; Macrófagos/metabolismo; Masculino; Nefrectomia/efeitos adversos; Ratos; Ratos Sprague-Dawley; Insuficiência Renal Crônica/metabolismo; Insuficiência Renal Crônica/patologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose / Transdução de Sinais / Inibidores de Proteínas Quinases / Insuficiência Renal Crônica / Cloridrato de Erlotinib Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Japão

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