Model selection based on combined penalties for biomarker identification.

Vradi, Eleni; Brannath, Werner; Jaki, Thomas; Vonk, Richardus

Vradi, Eleni; Brannath, Werner; Jaki, Thomas; Vonk, Richardus.

Afiliação

Vradi E; a Department of Research and Clinical Sciences Statistics , Bayer AG , Berlin , Germany.
Brannath W; b Institute of Statistics, Competence Center for Clinical Trials Bremen , Faculty 3, University of Bremen , Bremen , Germany.
Jaki T; c Department of Mathematics and Statistics , Medical and Pharmaceutical Statistics Research Unit, Lancaster University , Lancaster , United Kingdom.
Vonk R; a Department of Research and Clinical Sciences Statistics , Bayer AG , Berlin , Germany.

J Biopharm Stat ; 28(4): 735-749, 2018.

Article em En | MEDLINE | ID: mdl-29072549

Assuntos

Simulação por Computador/estatística & dados numéricos; Bases de Dados Factuais; Modelos Biológicos; Biomarcadores; Humanos

Palavras-chave

Biomarker panels; combined penalties; model selection; penalized regression; regularization; sparsity; stepwise variable selection; treatment responder

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Simulação por Computador / Bases de Dados Factuais / Modelos Biológicos Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha

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