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Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
Saberi, Shahram; Stauffer, Jennifer E; Jiang, Jie; Garcia, Sandra Diaz; Taylor, Amy E; Schulte, Derek; Ohkubo, Takuya; Schloffman, Cheyenne L; Maldonado, Marcus; Baughn, Michael; Rodriguez, Maria J; Pizzo, Don; Cleveland, Don; Ravits, John.
Afiliação
  • Saberi S; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Stauffer JE; Department of Pathology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy, Place Box 1194, New York, NY, 10029, USA.
  • Jiang J; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Garcia SD; Jackson Laboratory, 600 Main St, Bar Harbor, ME, 04609, USA.
  • Taylor AE; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Schulte D; Laboratory for Cell Biology, Ludwig Institute for Cancer Research, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0670, USA.
  • Ohkubo T; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Schloffman CL; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Maldonado M; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Baughn M; NeuroPace, Inc, 455 N. Bernardo Ave, Mountain View, CA, 94043, USA.
  • Rodriguez MJ; Department of Neurosciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0624, USA.
  • Pizzo D; Laboratory for Cell Biology, Ludwig Institute for Cancer Research, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0670, USA.
  • Cleveland D; Laboratory for Cell Biology, Ludwig Institute for Cancer Research, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0670, USA.
  • Ravits J; Department of Cellular and Molecular Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Acta Neuropathol ; 135(3): 459-474, 2018 03.
Article em En | MEDLINE | ID: mdl-29196813
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medula Espinal / Encéfalo / Dipeptídeos / Proteínas de Ligação a DNA / Proteína C9orf72 / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Medula Espinal / Encéfalo / Dipeptídeos / Proteínas de Ligação a DNA / Proteína C9orf72 / Esclerose Lateral Amiotrófica Idioma: En Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos