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Structure-Activity Relationship Studies on a Series of 3α-[Bis(4-fluorophenyl)methoxy]tropanes and 3α-[Bis(4-fluorophenyl)methylamino]tropanes As Novel Atypical Dopamine Transporter (DAT) Inhibitors for the Treatment of Cocaine Use Disorders.
Zou, Mu-Fa; Cao, Jianjing; Abramyan, Ara M; Kopajtic, Theresa; Zanettini, Claudio; Guthrie, Daryl A; Rais, Rana; Slusher, Barbara S; Shi, Lei; Loland, Claus J; Newman, Amy Hauck.
Afiliação
  • Zou MF; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
  • Cao J; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
  • Abramyan AM; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
  • Kopajtic T; Psychobiology Section, Molecular Neuropsychiatry Research Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 251 Bayview Boulevard, Baltimore, Maryland 21224, United States.
  • Zanettini C; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
  • Guthrie DA; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
  • Rais R; Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine , 855 North Wolfe Street, Baltimore, Maryland 21205, United States.
  • Slusher BS; Department of Neurology, Johns Hopkins Drug Discovery, The Johns Hopkins University School of Medicine , 855 North Wolfe Street, Baltimore, Maryland 21205, United States.
  • Shi L; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
  • Loland CJ; Molecular Faculty of Health and Medical Sciences, University of Copenhagen , DK-2200 Copenhagen, Denmark.
  • Newman AH; Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program, National Institutes of Health , 333 Cassell Drive, Baltimore, Maryland 21224, United States.
J Med Chem ; 60(24): 10172-10187, 2017 12 28.
Article em En | MEDLINE | ID: mdl-29227643
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Avaliação Pré-Clínica de Medicamentos / Proteínas da Membrana Plasmática de Transporte de Dopamina Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Relação Estrutura-Atividade / Avaliação Pré-Clínica de Medicamentos / Proteínas da Membrana Plasmática de Transporte de Dopamina Idioma: En Ano de publicação: 2017 Tipo de documento: Article País de afiliação: Estados Unidos